Am J Blood Res 2013;3(2):102-106
Review Article
Understanding basic steps to hematopoietic stem cell transplantation
evaluation
Melissa Logue, Bipin N Savani
Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt
University Medical Center, Nashville, TN, USA
Received March 25, 2013; Accepted April 15, 2013; Epub May 5, 2013; Published May 15, 2013
Abstract: We are celebrating one millionth transplant in year 2013! With continued improvement in hematopoietic cell
transplantation (HCT) outcome, the indications for HCT continue to grow. Furthermore the sources of stem cells and the
number of suitable matches are expanding. At the same time, modified transplantation regimens have facilitated safer
procedures despite increase in patient’s age and comorbidies. In the current era, any patient indicated for HCT has a stem
cell source and therefore steps to HCT and coordinated pre-transplant care is an integral part of management to improve
transplant outcome. This review discusses our approach to the transplant evaluation process and this article will serve as a
valuable tool for primary care physicians and referring hematologists/oncologists. (AJBR1303005).
Keywords: Transplantation, hematological malignancies, preparation, evaluation
Address correspondence to: Melissa Logue, NP, Hematology and Stem Cell Transplantation Section, Vanderbilt University
Medical Center and VAMC, 2665 The Vanderbilt Clinic, Nashville TN-37232-5505. Phone: 615-936-8422; Fax: 615-936-1812;
E-mail: Melissa.McGuire@Vanderbilt.Edu
Review Article
Understanding basic steps to hematopoietic stem cell transplantation
evaluation
Melissa Logue, Bipin N Savani
Hematology and Stem Cell Transplantation Section, Division of Hematology/Oncology, Department of Medicine, Vanderbilt
University Medical Center, Nashville, TN, USA
Received March 25, 2013; Accepted April 15, 2013; Epub May 5, 2013; Published May 15, 2013
Abstract: We are celebrating one millionth transplant in year 2013! With continued improvement in hematopoietic cell
transplantation (HCT) outcome, the indications for HCT continue to grow. Furthermore the sources of stem cells and the
number of suitable matches are expanding. At the same time, modified transplantation regimens have facilitated safer
procedures despite increase in patient’s age and comorbidies. In the current era, any patient indicated for HCT has a stem
cell source and therefore steps to HCT and coordinated pre-transplant care is an integral part of management to improve
transplant outcome. This review discusses our approach to the transplant evaluation process and this article will serve as a
valuable tool for primary care physicians and referring hematologists/oncologists. (AJBR1303005).
Keywords: Transplantation, hematological malignancies, preparation, evaluation
Address correspondence to: Melissa Logue, NP, Hematology and Stem Cell Transplantation Section, Vanderbilt University
Medical Center and VAMC, 2665 The Vanderbilt Clinic, Nashville TN-37232-5505. Phone: 615-936-8422; Fax: 615-936-1812;
E-mail: Melissa.McGuire@Vanderbilt.Edu
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